GLB1 Mouse Monoclonal Antibody [Clone ID: OTI10B2]

Specifications

Product Data
Clone Name	OTI10B2
Applications	IF, WB
Recommend Dilution	WB 1:200~2000, IF 1:100
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human GLB1(NP_001073279) produced in HEK293T cell.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72.6 kDa
Gene Name	galactosidase beta 1
Database Link	NP_001073279 Entrez Gene 12091 MouseEntrez Gene 316033 RatEntrez Gene 403873 DogEntrez Gene 709355 MonkeyEntrez Gene 2720 Human UniProt ID P16278
Background	This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Synonyms	EBP; ELNR1; MPS4B
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Galactose metabolism, Glycosaminoglycan degradation, Glycosphingolipid biosynthesis - ganglio series, Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism

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