TRK fused gene (TFG) Mouse Monoclonal Antibody [Clone ID: OTI2C3]

Specifications

Product Data
Clone Name	OTI2C3
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TFG(NP_001007566) produced in HEK293T cell.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	43.3 kDa
Gene Name	trafficking from ER to golgi regulator
Database Link	NP_001007566 Entrez Gene 360709 RatEntrez Gene 10342 Human UniProt ID Q92734
Background	There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq]
Synonyms	HMSNP; SPG57; TF6; TRKT3
Reference Data
Protein Pathways	Pathways in cancer, Thyroid cancer

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