Ornithine Decarboxylase (ODC1) Mouse Monoclonal Antibody [Clone ID: OTI1G6]

Specifications

Product Data
Clone Name	OTI1G6
Applications	FC, IF, WB
Recommend Dilution	WB 1:500~2000, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ODC1 (NP_002530) produced in HEK293T cell.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51.0 kDa
Gene Name	ornithine decarboxylase 1
Database Link	NP_002530 Entrez Gene 18263 MouseEntrez Gene 24609 RatEntrez Gene 4953 Human UniProt ID P11926
Background	This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq]
Synonyms	BABS; NEDBA; NEDBIA; ODC
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways

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