TPMT Mouse Monoclonal Antibody [Clone ID: OTI4B1]

CAT#: CF501069

Carrier-free (BSA/glycerol-free) TPMT mouse monoclonal antibody, clone OTI4B1 (formerly 4B1)

Formulation: Standard Carrier-Free



  View other "OTI4B1" antibodies (4)

Need it in bulk or conjugated?
Get a free quote

CNY 3,999.00


货期*
现货

规格
    • 100 ug

Product images

经常一起买 (2)
Biotinylation Labelling Kit formatted 4 x 0.05mg
    • 200 ug

CNY 3,170.00


HRP Conjugation kit for 0.2mg IgG
    • 200 ug

CNY 3,230.00

Specifications

Product Data
Clone Name OTI4B1
Applications IHC, WB
Recommend Dilution WB 1:2000, IHC 1:50
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human TPMT (NP_000358) produced in HEK293T cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 28.2 kDa
Gene Name thiopurine S-methyltransferase
Background This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Synonyms OTTHUMP00000016076; S-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine methyltransferase; thiopurine S-methyltransferase
Reference Data
Protein Families Druggable Genome
Protein Pathways Drug metabolism - other enzymes
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Other Versions

Customer Reviews 
Loading...