Cytokeratin 5 (KRT5) Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Frozen Sections: 1/100. Immunohistochemistry on Paraffin Sections: 1/50. Western Blot: 1/5000-1/10000 (ECL). Cytological material. Incubation time: 1 h at RT; extended with Paraffin.
Reactivity	Bovine, Human, Mouse
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Recombinant Human keratin K5.
Specificity	The antiserum reacts with basic keratin K5 (Mr 58 000; formerly also designated cytokeratin 5), expressed in basal and first suprabasal layers of epidermis. Highly specific staining pattern in human and murine skin.
Formulation	State: Serum State: Liquid Stabilized antiserum Stabilizer: 0.5% BSA Preservative: 0.09% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. Long term storage in aliquots at -20°C Avoid freeze/thaw cycles.
Gene Name	keratin 5
Database Link	Entrez Gene 3852 Human UniProt ID P13647
Background	Keratin K5 is expressed in the basal cells of the larynx, esophagus, trachea, bladder, prostate, cervix, vagina, breast acini, skin and sweat glands. In several studies the correlation between the expression of keratin K5 in different types of carcinomas (putatively derived from basal epithelial cells) and prognosis has been discussed (see references listed below).
Synonyms	KRT5, Cytokeratin-5, Keratin-5, Keratin 5, CK5, K5
Note	This antibody shows weak unspeific background staining in mouse brain, kidney and lung tissue.
Reference Data

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