Borrelia burgdorferi Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	Western blot.  Immunocytochemistry. Immunohistochemistry on Formalin-Fixed Paraffin Sections.
Reactivity	Borrelia burgdorferi
Host	Rabbit
Clonality	Polyclonal
Immunogen	Whole cell preparation from B. burgdorferi.
Specificity	Reactive Western blot bands at 83 kD, 41 kD, 34 kD, 31 kD and additional low MW bands. Cross-reacts with Treponema pallidum, B. hermsii and B. parkerii.
Formulation	PBS Label: HRP State: Liquid purified Ig fraction Stabilizer: 10 mg/ml BSA Preservative: 0.002% Thimerosal Label: Highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed Molar radio: Estimated molar HRP: IgG substitution is 2-3.
Concentration	lot specific
Conjugation	HRP
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Borrelia burgdorferi is a spirochete and the cause of Lyme disease, a tick transmitted illness of humans and animals. B. burgdorferi may persist in humans and animals for months or years following initial infection, despite a robust humoral immune response. B. burgdorferi resembles other spirochetes in that it is a highly specialized, motile, two-membrane, spiral shaped bacteria which lives primarily as an extracellular pathogen. B. burgdorferi has an unusual genome compared with other eubacteria which includes a linear chromosome approximately one megabase in size and numerous linear and circular plasmids.
Reference Data

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