WDHD1 Mouse Monoclonal Antibody [Clone ID: 23-5-14]

Specifications

Product Data
Clone Name	23-5-14
Applications	IF, IHC, IP, WB
Recommend Dilution	Immunofluorescence Microscopy. Immunoblotting: 1/3000 (ECL method). Immunoprecipitation. Immunohistochemistry on Frozen Sections: 1/300-1/500 (Fixation with Paraformaldehyde is recommended). Incubation Time: 1 h at RT.
Reactivity	Xenopus
Host	Mouse
Clonality	Monoclonal
Immunogen	Nuclear fraction prepared from Xenopus laevis oocytes.
Specificity	The antibody recognizes a 125 kDa Nucleoplasmic Protein AND1. Immunolocalization studies showed a dispersed, finely granular distribution pattern throughout the nucleoplasm.
Isotype	IgG1
Formulation	State: Supernatant State: Liquid Culture Supernatant Preservative: 0.09% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Database Link	UniProt ID O13046
Background	AND-1 (WDHD1) is a nuclear and nucleolar protein that contains multiple WD40 repeats, and one HMG region. AND-1 (WDHD1) has a predicted molecular weight of 126 kD and can form homodimers. WDHD1 is expressed in the brain, epidermis, liver, and stomach. During mitosis, AND-1 (WDHD1) is transiently expressed in nucleoplasm. AND-1 (WDHD1) can bind to DNA with high affinity and may be involved in protein-protein interactions. The role of AND-1 (WDHD1) is thought to be in chromatin assembly, transcription and DNA replication. AND-1 (WDHD1) has been reported to be phosphorylated on S1041.
Synonyms	AND1, AND-1
Reference Data

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