ICAM1 Mouse Monoclonal Antibody [Clone ID: MEM-111]

CAT#: BM2448PE

ICAM1 mouse monoclonal antibody, clone MEM-111, PE



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CNY 4,340.00


货期*
5周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name MEM-111
Applications FC
Recommend Dilution Flow cytometry: 20 µl reagent / 100 µl of whole blood or 10e6 cells in a suspension.
The content of a vial (2 ml) is sufficient for 100 tests.
Reactivity Bovine, Human, Rat
Host Mouse
Clonality Monoclonal
Immunogen Raji human Burkitt's lymphoma cell line
Specificity The antibody MEM-111 reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.
Formulation Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
Label: PE
State: Liquid Ig fraction
Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use
Conjugation PE
Storage Condition Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name intercellular adhesion molecule 1
Background CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
Synonyms ICAM-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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