Apolipoprotein A I (APOA1) Mouse Monoclonal Antibody [Clone ID: 1404]

CAT#: BM2157

Apolipoprotein A I (APOA1) mouse monoclonal antibody, clone 1404, Purified



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CNY 8,019.00


货期*
5周

规格
    • 1 mg

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Specifications

Product Data
Clone Name 1404
Applications ELISA, R
Recommend Dilution Competeitive RIA.
ELISA.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Purified human plasma Apo A-I
Specificity Hihgly specific for APO A-I, no cross reactivity with APO A-II or Apo B.
Formulation 0.015 M PBS, 0.15 M NaCl, pH 7.2 with 0.09 % Sodium Azide as preservative
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification DEAE-chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name apolipoprotein A1
Background Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease.
The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Synonyms APOA1, ApoA-I, Apo-AI, ApoAI
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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