CACNA1H (alpha-1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/200-1/2000. Immunohistochemistry: 1/50-1/500.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from N-term domain of Human CACNA1H protein.
Specificity	Reacts with Human 259 kDa CACNA1H protein.
Formulation	0.1M Tris, 0.1M Glycine and 2% Sucrose State: Purified State: Lyophilized purified powder Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized antibody at -20°C Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	calcium voltage-gated channel subunit alpha1 H
Database Link	Entrez Gene 8912 Human UniProt ID O95180
Background	Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an α1 subunit, an intracellular β subunit, a disulfide linked α2/δ subunit and a transmembrane γ subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
Synonyms	Cav3.2
Reference Data

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