TGM1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/200-1/1000. Immunohistochemistry: 1/100-1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 15 residue synthetic peptide derived from specific domain of Transglutaminase-1 protein.
Specificity	This antibody is specific to keratinocyte Transglutaminase 1.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized purified powder Preservative: None
Reconstitution Method	Restore in distilled water.
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Predicted Protein Size	90 kDa
Gene Name	transglutaminase 1
Database Link	Entrez Gene 7051 Human UniProt ID P22735
Background	Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is one of the more common disorders in Western countries.
Synonyms	Transglutaminase K, TGase K, KTG, Epidermal TGase
Reference Data

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