PLCZ1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, WB
Recommend Dilution	Western Blot. 1/100-1/1000. ELISA. Immunocytochemistry 1/50-1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptides derived frominternal parts of PLC-zeta-1
Specificity	This antibody reacts with human PLC zeta protein. No cross reaction.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Serum State: Lyophilized Powder
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Antiserum
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	phospholipase C zeta 1
Database Link	Entrez Gene 89869 Human UniProt ID Q86YW0
Background	The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.
Synonyms	Phospholipase C-zeta-1, Phospholipase C zeta 1, PLC-zeta-1
Reference Data

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