UQCRB (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500. Immunohistochemistry on paraffin sections: 1:10~50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human UQCRB
Specificity	This antibody detects UQCRB (Center).
Isotype	Ig
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	ubiquinol-cytochrome c reductase binding protein
Database Link	Entrez Gene 7381 Human UniProt ID P14927
Background	This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome.
Synonyms	UQBP, QP-C, Ubiquinol-cytochrome c reductase complex 14 kDa protein, Cytochrome b-c1 complex subunit 7
Note	Molecular Weight: 13530 Da
Reference Data
Protein Pathways	Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

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