TP53BP2 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 92-122 amino acids from the N-terminal region of human TP53BP2
Specificity	This antibody detects TP53BP2 (N-term).
Isotype	Ig
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	tumor protein p53 binding protein 2
Database Link	Entrez Gene 7159 Human UniProt ID Q13625
Background	TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	p53-binding protein 2, p53BP2, 53BP2, Bcl2-binding protein, BBP, NY-REN-51, ASPP2
Note	Molecular Weight: 125616 Da
Reference Data
Protein Families	Druggable Genome

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