RGS7 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500. Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 447-477 amino acids from the C-terminal region of Human RGS7.
Specificity	This antibody recognizes Human RGS7 (C-term).
Isotype	Ig
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	regulator of G-protein signaling 7
Database Link	Entrez Gene 6000 Human UniProt ID P49802
Background	RGS7 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations (By similarity).
Synonyms	OTTHUMP00000037994
Note	Molecular Weight: 57668 Da
Reference Data
Protein Families	Druggable Genome

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