PSTPIP1 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of Human PSTPIP1 / CD28P1
Specificity	This antibody recognizes Human PSTPIP1 / CD2BP1 (N-term).
Isotype	Ig
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	proline-serine-threonine phosphatase interacting protein 1
Database Link	Entrez Gene 9051 Human UniProt ID O43586
Background	The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Synonyms	PSTPIP, H-PIP, PAPAS, CD2BP1L, CD2BP1S, CD2-binding protein 1
Note	Molecular Weight: 47591 Da
Reference Data
Protein Families	Druggable Genome
Protein Pathways	NOD-like receptor signaling pathway

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