POMT1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1000.  Western Blot: 1/1000.  Flow Cytometry: 1/10-1/50.  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of Human POMT1
Specificity	This antibody recognizes Human POMT1 (C-term). Other species not tested.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	protein O-mannosyltransferase 1
Database Link	Entrez Gene 10585 Human UniProt ID Q9Y6A1
Background	The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.
Synonyms	FLJ37239; LGMD2K; RT
Note	Molecular Weight: 84909 Da
Reference Data
Protein Families	Transmembrane
Protein Pathways	O-Mannosyl glycan biosynthesis

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