NTH1 (NTHL1) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western blot: 1/100 - 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 95-126 amino acids from the Central region of human NTHL1
Specificity	This antibody reacts to NTHL1.
Isotype	Ig
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	34390 Da
Gene Name	nth-like DNA glycosylase 1
Database Link	Entrez Gene 4913 Human UniProt ID P78549
Background	The protein encoded by the NTHL1 gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity.
Synonyms	NTHL1, OCTS3
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Base excision repair

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