FBXW8 (Center) Rabbit Polyclonal Antibody

CAT#: AP51638PU-N

FBXW8 (Center) rabbit polyclonal antibody, Aff - Purified



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CNY 6,314.00


货期*
5周

规格
    • 400 ul

Product images

Specifications

Product Data
Applications FC, IHC, WB
Recommend Dilution ELISA: 1/1000.
Western Blot: 1/100 - 1/500.
Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 273-303 amino acids from the Central region of human FBXW8
Specificity This antibody reacts to FBXW8.
Formulation PBS
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.09% (W/V) sodium azide
Concentration lot specific
Purification Affinity chromatography on Protein A
Conjugation Unconjugated
Storage Condition

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Predicted Protein Size 67394 Da
Gene Name F-box and WD repeat domain containing 8
Background This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms F-box only protein 29, FBW6, FBW8, FBX29, FBXO29, FBXW6
Reference Data
Protein Families Druggable Genome
Protein Pathways Ubiquitin mediated proteolysis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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