DUOX2 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	Western Blot: 1/1000. Flow Cytometry: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2
Specificity	This antibody recognizes Human Dual oxidase 2 (Center).
Isotype	Ig
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein A followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	dual oxidase 2
Database Link	Entrez Gene 50506 Human UniProt ID Q9NRD8
Background	The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Synonyms	Large NOX 2, Long NOX 2, Thyroid oxidase 2, p138 thyroid oxidase, LNOX2, THOX2
Note	Molecular Weight: 175364 Da
Reference Data
Protein Families	Druggable Genome, Transmembrane

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