SPG3A (ATL1) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/100 - 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human ATL1
Specificity	This antibody reacts to Atlastin-1.
Isotype	Ig
Formulation	PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	atlastin GTPase 1
Database Link	Entrez Gene 51062 Human UniProt ID Q8WXF7
Background	The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms	ATL1, GBP3, GBP-3, Spastic paraplegia 3 protein A, GTP-binding protein 3
Note	Molecular Weight: 63544 Da
Reference Data
Protein Families	Druggable Genome, Transmembrane

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