Angiopoietin 2 (ANGPT2) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 409-440 amino acids from the C-terminal region of human ANGPT2
Specificity	This antibody reacts to Angiopoietin-2.
Isotype	Ig
Formulation	PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	angiopoietin 2
Database Link	Entrez Gene 285 Human UniProt ID O15123
Background	The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
Synonyms	ANG-2, ANG2, ANGPT2
Note	Molecular Weight: 56919 Da
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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