alpha 2 Macroglobulin (A2M) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western blotting: 1/100 - 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 1161-1192 amino acids from the C-terminal region of human A2M
Specificity	This antibody reacts to Alpha-2-macroglobulin.
Formulation	PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	alpha-2-macroglobulin
Database Link	Entrez Gene 2 Human UniProt ID P01023
Background	Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
Synonyms	Alpha-2-M, CPAMD5, Alpha 2 macroglobulin
Note	Molecular Weight: 163291 Da
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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