ATP6AP1 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blotting (0.2 - 1 µg/ml)
Reactivity	Canine, Equine, Human, Mouse, Rabbit, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide directed towards the middle region of human ATP6AP1
Formulation	State: Aff - Purified State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification	Purified using peptide immunoaffinity column
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Gene Name	ATPase H+ transporting accessory protein 1
Database Link	NP_001174 Entrez Gene 54411 MouseEntrez Gene 83615 RatEntrez Gene 537 Human UniProt ID Q15904
Background	This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.
Synonyms	V-ATPase subunit S1, Protein XAP-3, ATP6IP1, ATP6S1, VATPS1, XAP3
Reference Data
Protein Families	Transmembrane
Protein Pathways	Epithelial cell signaling in Helicobacter pylori infection, Lysosome, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection

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