STOM (N-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	Peptide ELISA: 1/128000 (Detection Limit). Western blot: 0.1-0.3 μg/ml. Approx 30kDa band observed in Human Erythroocytes, Spleen, Bone Marrow and Lung lysates (calculated MW of 31.7kDa according to NP_004090.4). Immunohistochemistry on Paraffin Sections: 5-10 µg/ml. In paraffin embedded Human Liver shows membrane staining of hepatocytes and of sinusoidal lining cells.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequencefrom the N-Terminus of the protein sequence according to NP_004090.4; NP_937837.1.
Specificity	This antibody is expected to recognize both reported isoforms (NP_004090.4; NP_937837.1).
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified IgG fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	stomatin
Database Link	Entrez Gene 2040 Human UniProt ID P27105
Background	Erythrocyte band 7 integral membrane protein isoform a, also known as STOM, is a member of a highly conserved family of integral membrane proteins. STOM may regulate ACCN1 and ACCN3 gating. It is a membrane protein involved in regulation of monovalent cation transport through lipid membranes. A second function of STOM may be to act as a cytoskeletal anchor. It is a major lipid-raft component of erythrocytes and epithelial cells, and is also an abundant platelet protein.
Synonyms	BND7, EPB72
Reference Data

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