Trpv3 (461-469) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA: 1:5,000 for detection of TRPV3 peptide (YRPREEEAI) coated on ELISA plate. Western blot: 1:2,000 to detect the 91kDa TRPV3 in mouse brain tissue extract.
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to amino acid 461-469 of mouse TRPV3, conjugated with KLH
Specificity	This antibody is reactive to the 91kDa TRPV3 from mouse brain tissue and other species with consensus TRPV3 sequence (YRPREEEAI).
Formulation	State: Azide Free State: Lyophilized Ig fraction
Reconstitution Method	Restore with double distilled water to adjust the final concentration to 1.00 mg/ml.
Purification	Protein G affinity
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	transient receptor potential cation channel, subfamily V, member 3
Database Link	Entrez Gene 246788 Mouse UniProt ID Q8K424
Background	Mouse transient receptor potential cation channel V3 (TRPV3) belongs to the family of transient receptor potential ion channels. The members of the family have similar tetramer structure and have shown polymodal activation. TRPV3 is a warmth sensor. It is activated at temperatures between 22 and 40 oC. TRPV3 is thought to be able to form hybrid channel with TRPV1 through hetero-assemble of the monomers. In human, the genes for TRPV3 and TRPV1 are located on chromosome 17.
Synonyms	VRL-3; VRL3
Reference Data

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