CEACAM1 (D1-4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, FC, WB
Recommend Dilution	Western blot: 1-5 μg/ml. ELISA: 1-5 μg/ml. FACS: 2-10 μg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Highly pure recombinant human soluble CEACAM-1 (D1-4)
Specificity	This antibody detects recombinant human soluble CEACAM-1. The antibody shows cross-reactivity with several other CEACAM familiy members. There is no cross-reactivity with human CEACAM-8.
Formulation	PBS pH 7.4 w/o preservative State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	Restore in sterile water to a concentration of 0.1-1.0 mg/ml.
Purification	Protein A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for one month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	carcinoembryonic antigen related cell adhesion molecule 1
Database Link	Entrez Gene 634 Human UniProt ID P13688
Background	Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.
Synonyms	BGP, BGP1, Biliary glycoprotein 1
Reference Data
Protein Families	Druggable Genome, Transmembrane

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