FGF1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1 μg/ml.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminal of human FGF1
Specificity	This antibody detects FGF acidic / FGF1 (C-term). No cross reactivity with other proteins.
Isotype	IgG
Formulation	0.2ml of distilled water will yield a concentration of 500μg/ml. State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	PA1311
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	fibroblast growth factor 1
Database Link	Entrez Gene 14164 MouseEntrez Gene 25317 RatEntrez Gene 2246 Human UniProt ID P05230
Background	Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q311. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm-and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.
Synonyms	FGFA, Acidic fibroblast growth factor, ECGF-beta, HBGF-1, HBGF1
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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