CD71 (TFRC) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: 1 μg/ml. Immunohistochemistry on Paraffin Sections: 1 μg/ml (Antigen Retrieval by heat is required).
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a sequence at the C-terminal of Human CD71
Specificity	This antibody detects CD71 / TFRC at C-term. No cross reactivity with other proteins.
Formulation	5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide State: Aff - Purified State: Lyophilized purified Ig fraction
Reconstitution Method	Restore with 0.2 ml of distilled water to a concentration of 0.5 mg/ml.
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody after reconstitution at 2-8°C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	transferrin receptor
Database Link	Entrez Gene 22042 MouseEntrez Gene 64678 RatEntrez Gene 7037 Human UniProt ID P02786
Background	CD71 is also known as transferrin receptor(TFRC). Nikinmaa and Schroder (1987) concluded that p90 and TFRC are the same protein: studies using monoclonal antibodies indicated that exhaustive precipitation of radioactively labeled lysates with one antibody removed all activity of lysates with the other. Peptide maps of antigens recognized with both antibodies showed great similarity and indicated that both antibodies react with the same antigen, the human transferrin receptor, but with different antigenic sites of the molecule. TFR is assigned to chromosome 3.
Synonyms	TfR1, p90, Transferrin receptor protein 1
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
Protein Pathways	Endocytosis, Hematopoietic cell lineage

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