PDGF beta (PDGFB) (222-233) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Human, Bovine, Sheep
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from C-Terminus of human PDGFB (NP_002599.1; NP_148937.1)
Specificity	This antibody detects PDGFB (C-term).
Formulation	Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	platelet derived growth factor subunit B
Database Link	Entrez Gene 5155 Human UniProt ID P01127
Background	PDGF-B is the major polypeptide mitogen in serum for cells of mesenchymal origin; it promotes cellular proliferation and inhibits apoptosis.
Synonyms	Platelet-derived growth factor subunit B, PDGF beta, PDGF B, PDGF-B, Platelet-derived growth factor beta, PDGF subunit B, Platelet-derived growth factor B chain, PDGF2, PDGF-2, c-Sis, SIS, Becaplermin
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma

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