Thrombospondin 1 (THBS1) (19-32) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Canine, Equine, Goat, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Bovine
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from N-Terminus of human THBS1 (NP_003237.2)
Specificity	This antibody detects Thrombospondin-1 (THBS1) at N-term.
Formulation	Tris saline, pH 7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	thrombospondin 1
Database Link	Entrez Gene 21825 MouseEntrez Gene 445442 RatEntrez Gene 7057 Human UniProt ID P07996
Background	Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors.
Synonyms	TSP, TSP1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Bladder cancer, ECM-receptor interaction, Focal adhesion, p53 signaling pathway, TGF-beta signaling pathway

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