Activin Receptor Type IA (ACVR1) (147-161) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 4 µg/ml. Western Blot: 0.3 - 1 µg/ml.
Reactivity	Canine, Human, Mouse, Rat, Bovine, Bat, Equine, Monkey, Porcine, Rabbit
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from an internal region of human ACVR1
Specificity	This antibody detects Activin receptor type 1 (ACRV1) at aa 147-161.
Formulation	Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	activin A receptor type 1
Database Link	Entrez Gene 11477 MouseEntrez Gene 79558 RatEntrez Gene 90 Human UniProt ID Q04771
Background	Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors.
Synonyms	Activin receptor type IA, ACVRLK2, ALK2, SKR1, ACRV1A
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

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