Superoxide Dismutase 1 (SOD1) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1,000. Western blot: 1/100 - 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide selected from the Center region of human SOD1
Specificity	This antibody reacts to Superoxide Dismutase 1 (SOD1).
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid purified Ig
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	superoxide dismutase 1, soluble
Database Link	Entrez Gene 6647 Human UniProt ID P00441
Background	SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.
Synonyms	SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases

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