SF2 (SRSF1) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western blotting: 1/50-1/100. Immunohistochemistry: 1/50-1/100.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 165~194 amino acids from the C-terminal region of Human SFRS1
Specificity	This antibody recognizes SFRS1.
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	serine/arginine-rich splicing factor 1
Database Link	Entrez Gene 6426 Human UniProt ID Q07955
Background	SFRS1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.
Synonyms	ASF, ASF-1, Alternative-splicing factor 1, SF2P33
Reference Data
Protein Families	Stem cell - Pluripotency
Protein Pathways	Spliceosome

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