IMPDH2 Rabbit Polyclonal Antibody

CAT#: AP17504PU-N

IMPDH2 rabbit polyclonal antibody



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CNY 6,160.00


货期*
5周

规格
    • 400 ul

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the Center region of human IMPDH2
Specificity This antibody reacts to IMPDH2.
Formulation PBS with 0.09% (W/V) sodium azide
State: Liquid purified Ig
Concentration lot specific
Purification Saturated Ammonium Sulfate (SAS) precipitation
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name IMP (inosine 5'-monophosphate) dehydrogenase 2
Background IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. Its gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Synonyms IMPD2, Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2, EC=1.1.1.205, IMPDH-II, IMPD-2
Reference Data
Protein Families Druggable Genome
Protein Pathways Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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