CREB3L1 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western blot: 1/50-1/100. Flow cytometry: 1/10-1/50. Immunohistochemistry: 1/50-1/100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 488~517 amino acids from the C-terminal region of Human CREB3L1
Specificity	This antibody detects CREB3L1 / OASIS at C-term.
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cAMP responsive element binding protein 3-like 1
Database Link	Entrez Gene 26427 MouseEntrez Gene 90993 Human UniProt ID Q96BA8
Background	CREB3L1 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It is specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). It may play a role in gliosis. In vitro, it binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
Synonyms	PSEC0238
Note	Calculated Molecular weight: 57005 Da
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Huntington's disease, Melanogenesis, Prostate cancer

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