ANGPTL3 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1:1000. ELISA: 1:1,000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 82-114 amino acids from the N-terminal region of human ANGPTL3
Specificity	This antibody detects Angiopoietin-5 at N-term.
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction
Concentration	lot specific
Purification	Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	angiopoietin like 3
Database Link	Entrez Gene 30924 MouseEntrez Gene 27329 Human UniProt ID Q9Y5C1
Background	ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Synonyms	ANGPTL3, ANGPT5, Angiopoietin-like 3, ANG5, ANG-5
Note	Molecular weight: 53637 Da
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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