LINC02210-CRHR1 (250-263) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC
Recommend Dilution	Peptide ELISA: 1/1000 (Detection Limit). Western Blot: Preliminary experiments in human colon, duodenum and placenta lysates gave no specific signal but low background (at antibody concentration up to 1 µg/ml). Immunohistochemistry on Paraffin Sections: 5 µg/ml. Paraffin embedded Human Brain (Cortex). Immunofluorescence on Mouse Prefrontal Cortical Neurons.
Reactivity	Bovine, Canine, Human, Mouse, Rat, Sheep
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence KLYYDNEKCWFGKR from the internal region of the protein sequence according to NP_004373.2.
Specificity	This antibody recognizes CRHR1 / CRF-R (250-263).
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	LINC02210-CRHR1 readthrough
Database Link	Entrez Gene 104909134 Human UniProt ID P34998
Background	CRF1 is a receptor for corticotropin releasing factor. It shows high affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Synonyms	CRHR-1, CRFR, CRFR1, CRHR, Corticotropin-releasing factor receptor 1, CRF-R, CRF1, Corticotropin-releasing hormone receptor 1, CRH-R 1
Reference Data

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