AMPK alpha 1 (PRKAA1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA 1:1,000. Western blot 1:50 - 1:100. Immunohistochemistry 1:10 - 1:50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S487 of human PRKAA1.
Specificity	This antibody detects AMPK alpha (PRKAA1).
Isotype	Ig
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	protein kinase AMP-activated catalytic subunit alpha 1
Database Link	Entrez Gene 5562 Human UniProt ID Q13131
Background	PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.
Synonyms	AMPK1, AMPK alpha-1 chain
Note	Molecular weight: 63878 Da
Reference Data

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