SLUG (SNAI2) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/10-1/50.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 98-129 amino acids from the Central region of Human SLUG.
Specificity	This antibody detects SLUG at center.
Isotype	Ig
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	snail family transcriptional repressor 2
Database Link	Entrez Gene 6591 Human UniProt ID O43623
Background	SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects.
Synonyms	SLUGH
Note	Molecular weight: 29986 Da
Reference Data

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