PINX1 (225-237) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: 1/16000. Western blot: Approx 40kDa band observed in lysates of cell lines A549, HepG2 and K562 (calculated MW of 37.0kDa according to NP_060354.4). Recommended concentration: 0.3 - 1.0 µg/ml.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-ESYLQPKAKRHTE, from the internal region of the protein sequence according to NP_060354.4.
Specificity	This antibody reacts to PINX1.
Formulation	Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	PIN2/TERF1 interacting, telomerase inhibitor 1
Database Link	Entrez Gene 54984 Human UniProt ID Q96BK5
Background	PINX1 (PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. It contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1 and has been shown to be a potent telomerase inhibitor and putative tumor suppressor.
Synonyms	Pin2-interacting protein X1, LPTL, LPTS
Reference Data

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