PLTP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 1/100. Western Blot: 1/200 - 1/1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide surrounding amino acid 473 of Human PLTP
Specificity	Recognizes Phospholipid Transfer Protein (PLTP).
Isotype	IgG
Formulation	PBS containing 1% BSA as stabilizer and 0.02% as Thimerosal as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C for Short term or at -70°C for Long term. Avoid repeated freezing and thawing.
Gene Name	phospholipid transfer protein
Database Link	NP_006218.1 Entrez Gene 18830 MouseEntrez Gene 5360 Human UniProt ID P55058
Background	PLTP is one of at least two lipid transfer proteins found in human plasma. This protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, it may be involved in cholesterol metabolism. Plasma phospholipid transfer protein (PLTP) plays a central role in regulating plasma HDL levels and distribution of HDL subpopulations. This regulation is evidenced in vivo by markedly reduced plasma HDL levels in PLTP gene knock-out mice. PLTP also facilitates free cholesterol influx into HDL.
Synonyms	Lipid Transfer Protein II
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	PPAR signaling pathway

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