Liver Carboxylesterase 1 (CES1) (533-544) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/8000. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 0.03 - 0.1 µg/ml.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from an internal region of Human CES1
Specificity	Recognizes internal region of Carboxylesterase 1 (CES1).
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	carboxylesterase 1
Database Link	Entrez Gene 1066 Human UniProt ID P23141
Background	The enzymes of the carboxylesterase family are widely distributed and can be found in the tissues of all animals. They differ in biochemical, immunological and genetic properties and play different roles depending on which part of the organism they are expressed in. In general, these carboxylesterases are responsible for detoxification, since they are able to degrade a number of exogenous compounds such as esters, amides and thioesters. Esterases cause esters to split into an acid and an alcohol within the human body, especially the ones found in nucleic acids (phosphodiester bonds) and lipids. Some types of esterase are found in lysozomes and are called acid hydrolase. Other types of esterase include: - Cholesterol esterase - Also referred to as cholesterol ester hydrolase and sterol esterase, cholesterol esterase is a form of esterase that occurs in the pancreas, the intestinal mucosa, the liver, and the kidney. It even occurs in the muscle. - Leukocyte esterase - Leukocyte esterase is used to determine whether or not white blood cells and irregularities that could cause infections are in the body. - Cholinesterase - Cholinesterase consists of acetylcholinesterase, which is found in the blood, and pseudocholinesterase, which is found in the blood plasma of the liver.
Synonyms	CES2, SES1, Liver carboxylesterase 1, HMSE, Egasyn, hBr1
Reference Data

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