IRF7 (C-term) Rabbit Polyclonal Antibody

CAT#: AP07762PU-N

IRF7 (C-term) rabbit polyclonal antibody, Purified



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CNY 5,511.00


货期*
5周

规格
    • 50 ug

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Western Blot: 1 - 2 µg/ml.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic Peptide corresponding to 14 amino acids near the carboxy-terminus of human IRF7.
Specificity This antibody reacts with Interferon Regulatory Factor 7 (IRF7).
Formulation Phosphate Buffered Saline PBS containing 0.02% Sodium Azide as preservative.
State: Purified
State: Liquid purified IgG fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or
(in aliquots) at -20°C for longer.
Dilute only prior to immediate use.
Avoid repeated freezing and thawing.
Gene Name interferon regulatory factor 7
Background Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes.
IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling (3,4). Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.
Synonyms IRF-7
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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