Melatonin Receptor 1B (MTNR1B) (N-Term, Extracel. Dom.) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	MTNR1B antibody was raised against synthetic 16 amino acid peptide from N-terminal extracellular domain of human MTNR1B.
Specificity	This antibody detects Melatonin Receptor Type 1B (MT2) (MTNR1B) at N-terminal extracellular domain.
Formulation	PBS containing 0.09% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing.
Gene Name	melatonin receptor 1B
Database Link	Entrez Gene 4544 Human UniProt ID P49286
Background	MTNR1B / MT2 is one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
Synonyms	MTNR1B
Reference Data

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