EMR2 (ADGRE2) (N-term, Extracel. Dom.) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 12 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	EMR2 antibody was raised against synthetic 19 amino acid peptide from N-terminal extracellular domain of human EMR2.
Specificity	This antibody detects EGF-Like Module-Containing Mucin-Like Receptor 2 (EMR2) at N-terminal extracellular domain.
Formulation	PBS containing 0.09% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Avoid repeated freezing and thawing.
Gene Name	adhesion G protein-coupled receptor E2
Database Link	Entrez Gene 30817 Human UniProt ID Q9UHX3
Background	ADGRE2 / EMR2 is a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains.
Reference Data

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