OGR1 (GPR68) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA. Immunohistochemistry on Paraffin Sections: 5 - 10 µg/ml.
Reactivity	Bat, Equine, Human, Bovine, Canine, Hamster, Marmoset, Monkey, Mouse, Porcine, Rabbit, Rat, Gorilla
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic 17 amino acid peptide from N-terminal domain of human GPR68 / OGR1
Specificity	This antibody detects OGR1 / GPR68 at N-term.
Formulation	PBS containing 0.09% Sodium azide as preservative State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Gene Name	G protein-coupled receptor 68
Database Link	Entrez Gene 8111 Human UniProt ID Q15743
Background	OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003).
Synonyms	Sphingosylphosphorylcholine receptor, G-protein coupled receptor 68, GPR12A
Reference Data

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