GRIA1 pSer831 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1:1000; detects a band of approximately 100 kDa in rat brain lysates.
Reactivity	Canine, Chicken, Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831.
Specificity	This antibody is specific for glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.
Isotype	IgG
Formulation	10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol State: Purified State: Liquid purified Ig
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	glutamate ionotropic receptor AMPA type subunit 1
Database Link	Entrez Gene 2890 Human UniProt ID P42261
Background	GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.
Synonyms	GluR-1, GRIA1, GLUH1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA1
Reference Data

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