LASS3 (CERS3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot (1:400 starting dilution).
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from human LASS3 protein
Specificity	This antibody detects Lass3. Expression of Lass3 appears to be solely limited to the testis.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Aff - Purified State: Liquid ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing.
Gene Name	ceramide synthase 3
Database Link	Entrez Gene 204219 Human UniProt ID Q8IU89
Background	LASS3 (Longevity Assurance homolog 3) is a member of a highly conserved family of proteins from yeast to humans which are involved in the synthesis of ceramide. Overproduction of LASS3 appears to results in increases in several ceramide species, with some preference toward those having middle to long chain fatty acid acyl-CoAs. Also appears to have (dihydro)ceramide synthesis activity. LASS3 expression appears to be limited almost solely to the testis.
Synonyms	LAG1 longevity assurance homolog 3
Reference Data

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