Sphk1 (Long Form) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: (1-5 µg/ml). Antibody has been tested on rat kidney lysate.
Reactivity	Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from the rat sphingosine kinase 1, long form, protein
Specificity	This antibody detetcs Sphingosine Kinase 1 (Long Form).
Formulation	Phosphate buffered saline with 0.08 % sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Ship on dry ice. Upon arrival, aliqout and store frozen at -20°C to -70°C. Avoid repeated freezing and thawing.
Gene Name	sphingosine kinase 1
Database Link	Entrez Gene 170897 Rat UniProt ID Q91V26
Background	Rat sphingosine kinase 1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (spp)(sphingosine + ATP = sphingosine 1-phosphate + ADP), a lipid mediator with both intra- and extracellular functions. also acts on d-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as d,l-threo-dihydrosphingosine, n,n-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. The long form of sphingosine kinase 1, an N-terminal extension, is responsible for FceRI-mediated calcium mobilization and may play a role in other ligand mediated signaling events.
Synonyms	SPHK, SPK, SPK 1, SPK-1
Reference Data

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